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O-Desmethyltramadol (O-DSMT, desmetramadol) is an opioid analgesic and an active metabolite which is produced in the liver after the consumption of tramadol. It has little to no history of human usage but is easily accessible through the use of certain online research chemical vendors. In comparison to tramadol, O-DSMT lacks any stimulation and feels considerably closer to that of a traditional opiate. It is also stronger in terms of its potency and has a significantly shorter duration.